Drugs that have been documented to cause problems in dogs with the MDR1 mutation
The Veterinary Clinical Pharmacology Lab (of the College of Veterinary Medicine) has released a study regarding the interactions of numerous drug interactions in dogs that carry the MDR1 mutation. Collies and other herding breeds are especially susceptible to side effects from these drugs. The interactions can cause side effects ranging from neurological toxicity to bone marrow suppression.
Please take the time to read the article below. We recommend that you print a copy, and ask your veterinarian to add it to your dog's file. Before allowing your dog to receive a medication, ask your vet to cross reference the article.
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